The methods of comparative effectiveness research.

Methods Reference Guide for Effectiveness and Comparative Effectiveness Reviews

Effectiveness and Comparative Effectiveness Reviews, systematic reviews of existing research on the effectiveness, comparative effectiveness, and comparative harms of different health care interventions, are intended to provide relevant evidence to inform real-world health care decisions for patients, providers, and policymakers. In an effort to improve the transparency, consistency, and scient...

A Comparative Study on the Effectiveness of Different Hand Disinfectant Solutions Used in Surgical Scrub

Background and Objectives: Hand hygiene is a crucial measure for preventing healthcare-related infections. Surgical scrub is an important factor in the safety and success of a surgical operation. The aim of this study was to comparatively evaluate effectiveness of some conventional surgical antiseptic solutions, and to identify the most effective one. Methods: Effectiveness of alcohol-based s...

A comparative study on the effectiveness of Acceptance and Commitment therapy and mindfulness therapy on cognitive emotion regulation of female adolescents with self-harming behaviors

The aim of the present study was to compare the effects of acceptance and commitment therapy and mindfulness therapy on the cognitive emotion regulation of female adolescents with self-harming behaviors. The present study is a quasi-experimental study with a pretest-posttest design with a control group. The study population consisted of all female students studying in the first secondary school...

Comparative effectiveness research priorities: identifying critical gaps in evidence for clinical and health policy decision making.

BACKGROUND In the debate on improving the quality and efficiency of the United States healthcare system, comparative effectiveness research is increasingly seen as a tool for reducing costs without compromising outcomes. Furthermore, the recent American Recovery and Reinvestment Act explicitly describes a prioritization function for establishing a comparative effectiveness research agenda. Howe...

A Comparative Study on the Effectiveness of Garlic with Clofibrate in the Treatment of Hyperlipidemia

Comparative Effectiveness and Caveat Emptor

Recent legislation has emphasized comparative effectiveness, including both the American Recovery and Reinvestment Act of 2009 and the Patient Protection and Affordable Care Act of 2010, which established the Patient Centered Outcomes Research Institute (PCORI) to foster comparative effectiveness research (CER).1,2 Defined as “the generation and synthesis of evidence that compares the benefits ...